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Oxaliplatin

CAS number: 63121-00-6
Formula: C8H14N2O4Pt
Mol. Mass: 397.2786 g/mol
Chemical Name: (R,R)-1,2-diaminocyclohexane(ethanedioate-O,O)platinum
About Oxaliplatin:
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as FOLFOX for the treatment of colorectal cancer. Compared to cisplatin the two ammine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility.
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Date 24 February, 2010

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